Equipment

Equipment

The central WCMC facility at the UC Davis Genome Center currently hosts 17 mass spectrometers (6 GC/MS and 11 LC/MS instruments), including seven accurate mass instruments for untargeted metabolomics and three triple quadrupole or QTRAP instruments for targeted analysis of low abundant metabolites.

In the Hammock, Newman and Taha research laboratories, another 10 mass spectrometers are available for comprehensive analysis of metabolism for both targeted and untargeted metabolomics.

11 LC-MS/MS instruments

5 ThermoFisher mass spectrometers

   3x Q-Exactive HF+ / Exploris orbital ion trap mass spectrometers with Vanquish UPLCs

   2x Altis triple quadrupole mass spectrometers with Vanquish UPLCs

3 Agilent mass spectrometers

   1x 6530 QTOF mass spectrometers with Agilent 1290 UPLC

   1x 6550 QTOF mass spectrometer with Agilent 1290 UPLC

   1x 6545 QTOF mass spectrometer with Agilent 1290 UPLC

2x Sciex mass spectrometers

    1x 6600 TripleTOF high resolution mass spectrometer with Sciex microUPLC and differential ion mobility interface

     1x QTRAP 6500+ with ThermoFisher Vanquish UPLC

1x Bruker mass spectrometer

   1x timsTOF Pro2 Flex mass spectrometer with Elute UPLC and MALDI interface for mass spectrometry-based imaging!

 

6 GC-MS instruments

5 LECO  mass spectrometers

   5x Pegasus III, IV and BT GC time of flight  mass spectrometers

 

All instruments are equipped with Agilent gas chromatographs and autosamplers.

1 Agilent mass spectrometers

  1x QTOF mass spectrometer for chemical or electron ionization, equipped with Agilent gas chromatographs and autosamplers.

Computational and Chemical Resources

The Metabolomics facility is supported by dedicated servers, tools and databases, including a 200 TB mirrored server for raw data storage. The facility stores over 4,500 unique metabolite standards. A range of -80°C and -20°C freezers in addition to grinders, homogenizers, sonicators, incubators, shakers and mixers are available for sample storage and processing.