ceramides, sphingomyelins, cholesteryl esters, lyso- and phospholipids, mono-, di- and triacylglycerols, galactosyl- and glucuronyllipids
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- For blood plasma, fecal matter, and tissue samples of various origins, normalized relative intensities are reported for up to 550 identified lipids in addition to unknowns. Lipids are identified by our mass spectral library of 400,000 MS/MS spectra in addition to accurate masses and retention time matching.
- Untargeted data processing may add a large number of additional metabolites of unknown chemical structure.
- Samples from other sources (tissues, urine, cell cultures) may differ in the number of identified and unidentified compounds.
- All lipids are reported by retention times, quantification masses, biochemical database identifiers and adduct information. Lipids are quantified by peak heights, not in absolute concentrations. However, we are adding 13 internal standards to convert peak heights into good estimates of absolute (micromolar) concentrations for a range of lipid classes typically detected in biofluids and tissues!