The central WCMC facility at the UC Davis Genome Center currently hosts 17 mass spectrometers (6 GC/MS and 11 LC/MS instruments), including seven accurate mass instruments for untargeted metabolomics and three triple quadrupole or QTRAP instruments for targeted analysis of low abundant metabolites.
In the Hammock, Newman and Taha research laboratories, another 10 mass spectrometers are available for comprehensive analysis of metabolism for both targeted and untargeted metabolomics.
11 LC-MS/MS instruments
5 ThermoFisher mass spectrometers
3x Q-Exactive HF+ / Exploris orbital ion trap mass spectrometers with Vanquish UPLCs
2x Altis triple quadrupole mass spectrometers with Vanquish UPLCs
3 Agilent mass spectrometers
1x 6530 QTOF mass spectrometers with Agilent 1290 UPLC
1x 6550 QTOF mass spectrometer with Agilent 1290 UPLC
1x 6546 QTOF mass spectrometer with Agilent 1290 UPLC
2x Sciex mass spectrometers
1x 6600 TripleTOF high resolution mass spectrometer with Sciex microUPLC and differential ion mobility interface
1x QTRAP 6500+ with ThermoFisher Vanquish UPLC
1x Bruker mass spectrometer
1x timsTOF Pro2 Flex mass spectrometer with Elute UPLC and MALDI interface for mass spectrometry-based imaging !
6 GC-MS instruments
5 LECO mass spectrometers
2x Pegasus III time of flight mass spectrometers
2x Pegasus IV time of flight mass spectrometers
1x BT time of flight mass spectrometer
All instruments are equipped with Agilent gas chromatographs and autosamplers.
1 Agilent mass spectrometers
1x QTOF mass spectrometer for chemical or electron ionization, equipped with Agilent gas chromatographs and autosamplers.
Computational and Chemical Resources
The Metabolomics facility is supported by dedicated servers, tools and databases, including a 200 TB mirrored server for raw data storage. The facility stores over 4,500 unique metabolite standards. A range of -80°C and -20°C freezers in addition to grinders, homogenizers, sonicators, incubators, shakers and mixers are available for sample storage and processing.