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Pilot Funding

This is the pilot grant page. Anyone can apply for a pilot grant at the metabolomic center if they want to study metabolomics.

UC Davis Campus Research Core Facilities
Pilot and Feasibility Projects

For UC Davis investigators, starting March 06, 2018 a new program has been issued for awards to pilot and feasibility projects.
Award preference will be given to projects that will generate long-term use, preliminary data for a new extramural grant or manuscript submissions.
Funding from this program will be granted to Academic Senate and Academic Federation members with PI status with the following constraints:

  • (1) Who have not used the requested facility in the past 2 years, or
  • (2) Investigators who will explore the utilization of equipment and services offered by the facility that they have not used before
  • These funds must be utilized within 12 months.
  • Please direct administrative questions to dmporter@ucdavis.edu .
  • The metabolomics core must provide an estimate for services that you apply for, so please contact metabolomics@ucdavis.edu before you apply to the Campus Program for pilot funds.

 

Application deadlines are

September 14, 2018

December 14, 2018

Specifically, UC Davis funds projects using underutilized services in the following areas:

(a) Stable isotope tracer studies (applications for this area must be directed to metabolomics@ucdavis.edu, not to dmporter@ucdavis.edu)
(b) Absolute quantification of amino acids in plasma using the EasyFaast kit
(c) Identification of unknown compounds on studies for which the metabolomics core has previously provided profiling data.
(d) Short chain fatty acids in fecal, cecal or intestinal matters.
(e) regular fee-based services as they are enrolled in the CRCF program

The applicant must include (at a minimum) the following information from the core facilty:

1.       Clearly identify enrolled service (non-enrolled services will no longer be followed up on by RCFP)

2.       Number of samples/animals/hours/etc. included in estimate

3.       Reason why the amount of samples/animals/hours/etc. is necessary

4.       Total estimated dollar value for each service included

5.       Signature and Print Name of CRCF Director or Staff

6.       (If applicable) Justification to fund existing user for newly developed service (details of service - when developed, new capability, etc.)

        UC Davis Genome Center
        Pilot and Feasibility Projects

        The Genome Center is soliciting applications for up to five small metabolomic pilot grants per year for up to $2,000 per project. Such grants are available for Principal Investigators located at UC Davis, but outside regional scientists are not eligible. The intent of such startup grants is to obtain data for NIH grant submissions. Project submissions can be sent any time to ofiehn@ucdavis.edu; reviews will be scored by NIH criteria (significance, investigator, innovation, approach, environment). Leveraging with other funding mechanisms, including other Genome Center core pilot grants, is most welcome.

        Former NIH Common Fund pilot & feasibility projects (closed)

        Funded Projects 2017

        After a thorough three-tiered review and decision process, we congratulate the following applicants to receive funding for their pilot grant application with the West Coast Metabolomics Center at UC Davis.

        George Thomas, Oregon Health Sci University
        To Study Treatment-Induced Autophagic Metabolic Reprogramming

        Andrew DeFilippis, U Kentucky, Louisville
        Targeted Plasma Metabolomic Profiling of Thrombotic Myocardial Infarction

        Valentina Medici, UC Davis
        Identification of Unique Metabolite Networks between Latino and Caucasian Patients with Nonalcoholic Fatty Liver Disease

        James Borneman, UC Riverside
        Integrated Metabolomic Analysis of Host and Microbiome in Mouse Intestines

        Ulrike Luderer, UC Irvine
        The Exposome and Reproductive Function in Women

        Manuela Martins-Green, UC Riverside
        Combined Metabolomics and Lipidomics Studies in Chronic Wound Initiation and Development

        Nancy Keim, UC Davis and WHNRC
        Lipidomics Network Indicative of Metabolic Inflexibility in Women at High Risk for Type 2 Diabetes

        Maria Roselle Abraham, Johns Hopkins University
        Investigation of Metabolism in Hypertrophic Cardiomyopathy

        Biswapriya Misra, Texas Biomedical Research Institute
        Lipidomics and Exposomics of Atherosclerotic Baboon Livers for Biomarker Discovery

        David Asmuth, UC Davis
        Impact of Antiretroviral Therapy on Vitamin D Concentrations in HIV-Infected Patients Employing a Novel Method for Vitamin D Measurement

        Funded Projects 2016

        After a thorough three-tiered review and decision process, we congratulate the following applicants to receive funding for their pilot grant application with the West Coast Metabolomics Center at UC Davis.

        Scott Damrauer, U Pennsylvania
        Supervised Exercise Training for Peripheral Artery Disease

        Jang Youn, U Southern California
        Dietary Potassium + Gut Microbiota in Postprandial Oxidative Stress

        Sean Wilson, Loma Linda U
        Maternal Hypoxemia and Oxidative Stress

        Stephan Lange, UC San Diego
        Inflammatory Resolution in Cardiometabolic Health and Disease

        Kip Connor, Harvard U
        Attenuation of Choroidal Neovascularization

        Jan Nolta, UC Davis
        Metabolic Modulation of Mesenchymal Stem Cells

        Joanna Chiu, UC Davis
        Cross-talk between Animal Circadian Clock and Metabolism

        Angela Zivkovic, UC Davis
        The Interplay of Diet and the Gut Microbiome In TMAO Production

        Funded Projects 2015

        After a thorough three-tiered review and decision process, we congratulate the following applicants to receive funding for their pilot grant application with the West Coast Metabolomics Center at UC Davis.

        Suzan Carmichael, Stanford University
        "Etiologies of Preterm Delivery Among Obese Women".

        John Sundberg, Jackson Laboratory
        "Lipids and Cicatricial Alopecias in Mice and Humans"

        Mark Sarzynski, LSU Pennington
        "Changes in the Metabolome and Lipidome in Response to Exercise Training"

        Kit Lam, UC Davis
        "Effect of the Tumor Microenvironment and Cancer Therapies on Exosomal Bioactive Lipid Profiles"

        Vimal Selvaraj, Cornell University
        "Lipid profiles in Alzheimer's disease".

        Aimee Edinger, UC Irvine
        "Effect of Anti-Neoplastic Sphingolipids on the Metabolome of Normal and Cancer Cells"

        Katrine Whiteson, UC Irvine
        "Integrative ‘Omics to Study Human-Associated Microbial Communities"

        Amir Zeki, UC Davis
        "Statin Immuno-Metabolomics in Asthma"

        Funded Projects 2014

        After a thorough three-tiered review and decision process, we congratulate the following applicants to receive funding for their pilot grant application with the West Coast Metabolomics Center at UC Davis.

        Erwin Berthier with Nancy Keller, University of Wisconsin
        "Aspergillus fumigatus Oxylipins Disrupt Host Immune Eicosanoid Signaling"

        Nick Kenyon, UC Davis
        "Profiling of Downstream Metabolites of L-Arginine in Severe Asthmatics"

        Frances Sladek, UC Riverside
        "Integrated Analysis of the Factors Driving Soybean Oil-induced Metabolic Syndrome in Mice"

        Stephen Wedgwood, UC Davis
        "Metabolomics of Neonatal Pulmonary Hypertension"

        Olivia Osborn, UC San Diego
        "Metabolite Changes Associated with Obesity and Weight Loss"

        Funded Projects 2013

        After a thorough three-tiered review and decision process, we congratulate the following applicants to receive funding for their pilot grant application with the West Coast Metabolomics Center at UC Davis.

        Graeme Bell, University of Chicago
        "Combined Metabolomics and Lipidomics of Type 1 Diabetes"

        Michele La Merrill, UC Davis
        "Dysfunctional Lipid Metabolism Underlies the Effect of Perinatal DDT Exposure on the Development of Metabolic Syndrome "

        Ernst Lengyel, University of Chicago
        "A Study of Changes in Lipid Metabolism of Ovarian Cancer Cells Co-Cultured with Adipocytes"

        Peter Kaiser, UC Irvine
        "Metabolite Changes Associated with Methionine Stress Sensitivity of Cancer"

        Roel Ophoff, UC Los Angeles
        "Biomarkers for Depression in CSF and Plasma in a Population Sample"

        Pei-an Shih, UC San Diego
        "Quantitative Profiling of Eicosanoids to Explore Molecular Mechanisms Underlying Anorexia Nervosa"

        Patricia Thompson, Jessica Anne Miller University of Arizona
        "Application of Oxylipin Metabolomics to a Celecoxib Intervention in Men at Risk for Colorectal Neoplasia Recurrence"

        Johanna Lampe, Fred Hutchinson Cancer Research Center at Univ. of Washington, Seattle
        "Metabolic Profiling of Visceral and Subcutaneous Adipose Tissue from Colorectal Cancer Patients: Unraveling the Link Between Adipose Tissue and Cancer"

        Rudy Ortiz, UC Merced
        "Metabolomic and Lipidomic Profiles in Response to Exogenous Insulin and GLP-1 Infusions during Prolonged Fasting"

        Patricia Oteiza, UC Davis
        "Disruption of Zinc Homeostasis can Impair Maternal Glucocorticoid Metabolism: Consequences on the Developing Fetus"

        Vivian Hook, UC San Diego
        "Metabolomics Analyses of Neurotransmitter Profiles Regulated in Schizophrenia Modeled in Human Induced Pluripotent Stem Cells"

        Jayoung Kim, Cedars-Sinai Medical Center, Los Angeles
        "Urinary Metabolites in IC/PBS Diagnosis"

         

        For more information, contact  metabolomics@ucdavis.edu

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